Azithromycin dihydrate 117772-70-0
Product Description
Product Name | Azithromycin dihydrate |
Synonyms | AZITHROMYCIN 2-HYDRATE;1-Oxa-6-azacyclopentadecan-15-one, 13-(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyloxy-, dihydrate,( 58045766,2R,3S,4R,5R,8;AZITHROMYCINDIHYDRATE(PATENTED-NOSUPPLY);1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, dihydrate,( 58045767,2R,3S,4R,5R,8R,10R;1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, dihydrate, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-;azithromycin hydrate;Azithromycin (100 mg);(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptaMethyl-11-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one Dihydrate |
CAS | 117772-70-0 |
MF | C38H72N2O12 |
MW | 748.99 |
EINECS | 1592732-453-0 |
Product Categories | Macrolides (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Carbohydrates & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Pfizer compounds;Pharmaceuticals;SELDANE;Inhibitors |
application | For respiratory infections, urinary tract infections, skin and soft tissue infections and sexually transmitted diseases |
Melting point | 126 C |
Boiling point | 717℃ |
alpha | D26 -41.4° (c = 1 in CHCl3) |
refractive index | 47 ° (C=2, EtOH) |
RTECS | RN6960000 |
Fp | >110°(230°F) |
storage temp. | -20°C Freezer |
solubility | Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride |
Merck | 14,915 |
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | A White or almost white crystalline powder | Conforms |
Solubility | Practically insoluble in water,freely soluble in anhydrous ethanol and in methylene chloride | Conforms |
Identification | IR | Conforms |
HPLC | ||
Crystallinity | Meet the requirements | Conforms |
PH | 9.0 ~ 11.0 | 9.9 |
Related substances | Desosaminylazithromycin ≤0.3% | DL |
N-demethylazithromycin ≤0.7% | 0.001 | |
Any other single impurity ≤1.0% | Conforms | |
Total impurities≤3.0 % | 0.015 | |
Residual solvents | Acetone ≤0.5% | 0.003 |
Loss on drying | 4.0 % ~ 5.0% | 0.045 |
Residue on Ignition | ≤0.3% | 0.0004 |
Melting point | 50 °C ~ 60 °C | 50 °C ~ 60 °C |
Sulphate ash | ≤0.1% | 0.0005 |
Heavy metals | ≤ 25 ppm | NMT25 ppm |
Assay ( calculated on the anhydrous basis) | 945 ug ~ 103 ug of azithromycin per mg | 982 ug/ mg |
Conclusiion | This product complied with the standard of Enterprise/USP |
Product Categories : Health & Medical > Pharmaceutical
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